Nootropic peptide

SEMAX

Russian nootropic peptide studied for raising neurotrophic factors (BDNF, NGF) and for its neuroprotective action.

CognitiveNeuroprotection

Synthetic analog of the ACTH(4-10) fragment, developed in Russia as a nootropic. It is studied for its effect on the expression of neurotrophic factors such as BDNF and NGF, and for its neuroprotective activity at the transcriptomic level in cerebral ischemia models.

Research objectives
99% purity (HPLC)
Lyophilized vial for reconstitution
Refrigerate · protect from light
Size (dose)
Quantity
$130
$130 each · 10 mg
Add 2 more and get 10% volume discount.
Sold for research use only (RUO). Not for human or veterinary use.

Benefits studied in research

  • Studied for its effect on the expression of neurotrophic factors such as BDNF and NGF.
  • Investigated for its role in cognitive function and memory processes in experimental models.
  • Evaluated for its neuroprotective activity against stress conditions in preclinical models.
  • In cerebral ischemia-reperfusion models, studied for neuroprotective effects at the transcriptomic level.

Key data

Class
Nootropic peptide (ACTH 4-10 analog)
Markers
BDNF · NGF
Study focus
Cognition · memory · neuroprotection
Models
Preclinical (ischemia, stress)
Storage
−20 °C lyophilized · 4 °C reconstituted

Scientific backing

Peer-reviewed publications on the molecule. Research references, not indications for use.

Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
Brain Research · 2006 · Dolotov OV, Karpenko EA, Inozemtseva LS, et al.
View publication
Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide Following Cerebral Ischaemia-Reperfusion in Rats
Genes (Basel) · 2020 · Filippenkov IB, Stavchansky VV, et al.
View publication

Reconstitution calculator

Adjust the values to plan your protocol. The vial's mg sync with the size you select above.

5 mg/ml
5,000 mcg/ml
Concentration
5 U
In the syringe (U-100)
0.05 ml
Volume per dose
40
Doses per vial

Calculation tool for laboratory planning (RUO). An insulin U-100 syringe has 100 units = 1 ml. Not a dosing recommendation.

Frequently asked questions

A peptide studied for its effect on cognitive processes. In this case, research focuses on the modulation of neurotrophic factors such as BDNF and NGF.

Beyond the lyophilized vial, it appears frequently in the literature in intranasal form in experimental models.

Also in this line

Related products