Reference protocol: Ipamorelin + CJC-1295

First time? Start here

Your Ipamorelin + CJC-1295 vial arrives with the compound as a dry powder. Before using it you mix it with a special water — that step is called reconstitution — and measure each dose with an insulin syringe. Here is everything you need, in order.

1. Get what you need: your vial, a vial of bacteriostatic water (not included — it is the special mixing water), a 1 ml U-100 insulin syringe — ask for it exactly like that at any pharmacy — and alcohol wipes.
2. Mix the powder with the water (reconstitute): the vial is never uncapped — the needle goes through the rubber stopper. Add 2.5 ml of water letting it run down the inside wall, then swirl gently — never shake; it turns clear in a few minutes (some compounds take longer). Measure the water with the same insulin syringe: full to the top is 1 ml — repeat until you complete the 2.5 ml. Once mixed, the vial goes in the fridge and lasts about 4 weeks; unmixed, also keep it refrigerated from the day it arrives.
3. Fill the syringe up to the 6 mark: every small line on the insulin syringe is 1 unit (U). That mark equals the starting dose (240 mcg); if your dose is different, pick it in the panel below and the number updates. And note: several protocols raise the dose after the first weeks — the dose steps further down tell you when your mark changes.
4. Inject under the skin and you are done: belly area (two fingers away from the navel), skin cleaned with alcohol; pinch the skin, insert the full needle and inject slowly. Switch sides each time and use a new syringe for every injection. Used right before bed, 2–3 hours after your last meal.

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Quick facts

Why this blend takes 2.5 ml of water

Our house 1-to-1 rule would leave this 10 mg vial at 10 mg/ml, where the starting dose of 240 mcg is 2.4 units: a mark too fine to read with confidence on any syringe. For this product we recommend 2.5 ml of bacteriostatic water — it lands at 4 mg/ml — and the same doses become thick, legible marks: 240 mcg is 6 units.

Reconstitution and syringe units

For this product we recommend 2.5 ml of bacteriostatic water for the 10 mg vial: it sits at 4 mg/ml (this page explains why).

Timing and technique matter

• Before bed, after 2–3 hours without food: the GH pulse it stimulates occurs during deep sleep, and a recent meal — the elevated insulin — blunts it. Do not eat after the dose.
• The documented alternative is upon waking, before breakfast, if the nighttime dose does not fit your routine.
• Inject SLOWLY: rapid administration produces warmth, flushing, and a pins-and-needles sensation on the skin. It is transient, but almost entirely avoided by injecting slowly.

What No-DAC means

CJC-1295 exists in two versions. The DAC version binds to albumin and keeps GH elevated for days with a single dose — at the cost of the documented risk of desensitization from constant stimulation. The version without DAC (the one in our blend) has a half-life of about 30 minutes and produces a 2 to 3 hour pulse that mimics natural secretion: that is why it is dosed daily and why timing weighs so heavily on the result.

Documented precautions

• Reported effects: fluid retention, swelling, increased appetite, mild fatigue after the dose, headache, flushing or warmth when injecting fast.
• It can transiently reduce insulin sensitivity: caution and monitoring with glucose alterations or glucose-lowering medication.
• Corticosteroids at high or chronic doses blunt GH release and reduce the blend's effectiveness.
• Contraindicated with active cancer (including pituitary adenomas), untreated hypothyroidism, pregnancy, and breastfeeding.

In our catalog

The 10 mg blend (5 + 5) is on the Ipamorelin + CJC-1295 product page. In documented research practice it is combined with Tesamorelin for synergistic GH elevation, and with BPC-157 + TB-500 for connective tissue recovery.